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Description

Nicotinamide Riboside Pro Complete represents a comprehensive, systems-level approach to healthy aging through three synergistic pathways: NAD+ production, methylation support, and sirtuin activation.

This doctor-formulated trio addresses cellular aging at its core by targeting the interconnected processes that naturally decline over time.

NAD+ is a critical coenzyme found in every cell that powers hundreds of metabolic processes, including energy production, DNA repair, and cellular communication.

NAD+ levels decline by approximately 50% by midlife, which accelerates cellular aging and impairs mitochondrial function.

Nicotinamide Riboside is a highly efficient NAD+ precursor that converts directly into NAD+ through a two-step enzymatic pathway, effectively replenishing declining levels to support cellular energy metabolism, genomic stability, and neurological function.

Trans-Resveratrol is a powerful polyphenol that activates sirtuins—proteins often called "longevity genes" that regulate cellular health and lifespan. Sirtuins require NAD+ as their fuel source, making the combination of NR and resveratrol synergistic.

This micronized form ensures superior absorption and bioavailability.

Together, NR and resveratrol work like a car: NR provides the fuel while resveratrol acts as the accelerator, amplifying the body's natural cellular defense and repair systems.

TMG (Trimethylglycine) serves as a methyl donor to support the body's methylation processes—critical biochemical reactions that regulate gene expression, neurotransmitter production, and cardiovascular health.

When taking NAD+ precursors, the body uses methyl groups to metabolize certain byproducts.

TMG helps maintain an adequate methyl pool while converting homocysteine into beneficial methionine, supporting heart health and liver function.

How to use

Take 2 capsules daily with or without food, or as directed by your healthcare professional.

For optimal results, take consistently at the same time each day, preferably in the morning.

NAD+ levels may begin increasing within 2 weeks of consistent use.

Not intended for use by pregnant or nursing women or children.

Ingredients

Nicotinamide Riboside Hydrogen Malate (NR), Micronized Trans-Resveratrol (from Japanese Knotweed root), Trimethylglycine (TMG/Betaine Anhydrous), Microcrystalline Cellulose, Vegetable Capsule

NR Pro Complete

ProHealth Longevity

Doctor-formulated trio combining 500mg NR, 500mg trans-resveratrol, and 250mg TMG to boost NAD+ levels, activate longevity pathways, and support healthy ag

  • Comprehensive NAD+ Restoration
  • Sirtuin Pathway Activation
  • Methylation Cycle Support
  • Multi-System Aging Defense
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Description

Nicotinamide Riboside Pro Complete represents a comprehensive, systems-level approach to healthy aging through three synergistic pathways: NAD+ production, methylation support, and sirtuin activation.

This doctor-formulated trio addresses cellular aging at its core by targeting the interconnected processes that naturally decline over time.

NAD+ is a critical coenzyme found in every cell that powers hundreds of metabolic processes, including energy production, DNA repair, and cellular communication.

NAD+ levels decline by approximately 50% by midlife, which accelerates cellular aging and impairs mitochondrial function.

Nicotinamide Riboside is a highly efficient NAD+ precursor that converts directly into NAD+ through a two-step enzymatic pathway, effectively replenishing declining levels to support cellular energy metabolism, genomic stability, and neurological function.

Trans-Resveratrol is a powerful polyphenol that activates sirtuins—proteins often called "longevity genes" that regulate cellular health and lifespan. Sirtuins require NAD+ as their fuel source, making the combination of NR and resveratrol synergistic.

This micronized form ensures superior absorption and bioavailability.

Together, NR and resveratrol work like a car: NR provides the fuel while resveratrol acts as the accelerator, amplifying the body's natural cellular defense and repair systems.

TMG (Trimethylglycine) serves as a methyl donor to support the body's methylation processes—critical biochemical reactions that regulate gene expression, neurotransmitter production, and cardiovascular health.

When taking NAD+ precursors, the body uses methyl groups to metabolize certain byproducts.

TMG helps maintain an adequate methyl pool while converting homocysteine into beneficial methionine, supporting heart health and liver function.

How to use

Take 2 capsules daily with or without food, or as directed by your healthcare professional.

For optimal results, take consistently at the same time each day, preferably in the morning.

NAD+ levels may begin increasing within 2 weeks of consistent use.

Not intended for use by pregnant or nursing women or children.

Ingredients

Nicotinamide Riboside Hydrogen Malate (NR), Micronized Trans-Resveratrol (from Japanese Knotweed root), Trimethylglycine (TMG/Betaine Anhydrous), Microcrystalline Cellulose, Vegetable Capsule

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ProHealth Longevity

The Only Clinically-Proven NMN That Works

ProHealth Longevity has been trusted since 1988 with 33 consecutive years of A+ BBB ratings. Their Uthever NMN is the only NMN proven to boost NAD+ in clinical trials.

In a double-blind study, their NMN increased NAD+ levels by 38% - equivalent to reversing biological age by 12 years. Third-party tested for purity against fake NMN flooding the market.
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Nicotinamide Riboside Pro Complete

Frequently Asked Questions

What makes this different from taking NMN?

NR (Nicotinamide Riboside) and NMN are both NAD+ precursors, but NR has a unique advantage: it can enter cells directly through specific transport proteins without needing to be converted first.

This formula uses NR Hydrogen Malate, a stabilized form that's been extensively studied in human clinical trials with proven safety and efficacy.

Additionally, this complete formula includes trans-resveratrol and TMG, which NMN products typically lack, providing synergistic support for sirtuin activation and methylation—making it a more comprehensive longevity solution.

Why do I need TMG with NAD+ boosters?

When your body metabolizes NAD+ and its byproducts, it uses methyl groups—essential molecules needed for thousands of other critical functions including DNA regulation, neurotransmitter production, and cardiovascular health.

TMG acts as a "methyl donor" to replenish this methyl pool, preventing depletion that could occur with NAD+ supplementation alone.

Additionally, TMG converts homocysteine (an inflammatory amino acid linked to cardiovascular issues) into methionine, supporting heart and vascular health.

Many longevity experts, including Dr. David Sinclair, consider TMG essential when taking NAD+ precursors.

How long before I notice results after using this?

NAD+ levels begin rising at the cellular level within days of starting supplementation, with measurable increases typically seen within 2 weeks.

However, outward effects vary by individual.

Some people report increased energy and mental clarity within the first few weeks, while others notice improvements in exercise recovery, sleep quality, or cognitive function over 1-2 months.

For comprehensive cellular health benefits—including DNA repair, mitochondrial optimization, and metabolic improvements—consistent daily use for at least 8-12 weeks is recommended to experience the full spectrum of effects.

Can I take this long-term?

Yes, this formula is designed for long-term daily use to maintain optimal NAD+ levels and support healthy aging.

Clinical studies on NR have demonstrated safety at doses up to 2,000mg daily, and the 500mg dose in this formula is well within established safety parameters.

Trans-resveratrol and TMG also have extensive safety profiles supported by research.

Many users take this combination for years as part of their longevity regimen.

The formula is third-party tested and GMP certified.

As with any supplement regimen, consult your healthcare provider, especially if you have medical conditions or take medications.