Description
Description
What It Is
ProHealth NR Pro 500 combines two powerful longevity ingredients: Nicotinamide Riboside (NR) and TMG.
NR is a form of vitamin B3 that your body converts into NAD+, a molecule that naturally declines as we age.
By middle age, your NAD+ levels can drop by 50%, affecting energy, brain function, and cellular health.
This formula also includes TMG to support your body's methylation—important processes that keep your cells functioning properly.
How It Works Simply
Think of NAD+ as your cellular battery. NR recharges this battery by boosting NAD+ levels, which helps your cells produce energy, repair DNA, and function optimally.
Research shows NR starts working within 24 hours and builds up over weeks.
TMG acts as a support player, providing methyl groups that your body needs when processing NAD+.
This combination ensures you're not just boosting NAD+, but doing it in a balanced, sustainable way.
Proven Results
Clinical studies show people taking NR experience improved energy levels, better cognitive function, and enhanced cellular health.
One study found adults taking 1,000mg NR for 30 days had increased brain NAD+ levels and improved mental performance.
The addition of TMG supports heart health by managing homocysteine levels and protects your liver function.
How to use
How to use
Take two capsules daily with or without food, preferably in the morning to support daytime energy levels.
Consistency is key—NR begins boosting NAD+ levels within 24 hours, with substantial increases observed over days to weeks in a dose-dependent manner.
For optimal results, take at the same time each day as part of your longevity wellness routine.
Can be combined with other longevity supplements like resveratrol for synergistic effects.
Ingredients
Ingredients
Nicotinamide Riboside (as NR Hydrogen Malate) 500mg, Trimethylglycine (TMG) 250mg, Vegetable Cellulose (capsule), Microcrystalline Cellulose
NR Pro 500 + TMG
Premium NAD+ booster combining 500mg Nicotinamide Riboside with 250mg TMG for optimal cellular energy, methylation support, and healthy aging pathways.
- Cellular NAD+ Restoration
- Cognitive Function & Neuroprotection
- Methylation Pathway Support
- Mitochondrial Performance & Energy
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Description
Description
What It Is
ProHealth NR Pro 500 combines two powerful longevity ingredients: Nicotinamide Riboside (NR) and TMG.
NR is a form of vitamin B3 that your body converts into NAD+, a molecule that naturally declines as we age.
By middle age, your NAD+ levels can drop by 50%, affecting energy, brain function, and cellular health.
This formula also includes TMG to support your body's methylation—important processes that keep your cells functioning properly.
How It Works Simply
Think of NAD+ as your cellular battery. NR recharges this battery by boosting NAD+ levels, which helps your cells produce energy, repair DNA, and function optimally.
Research shows NR starts working within 24 hours and builds up over weeks.
TMG acts as a support player, providing methyl groups that your body needs when processing NAD+.
This combination ensures you're not just boosting NAD+, but doing it in a balanced, sustainable way.
Proven Results
Clinical studies show people taking NR experience improved energy levels, better cognitive function, and enhanced cellular health.
One study found adults taking 1,000mg NR for 30 days had increased brain NAD+ levels and improved mental performance.
The addition of TMG supports heart health by managing homocysteine levels and protects your liver function.
How to use
How to use
Take two capsules daily with or without food, preferably in the morning to support daytime energy levels.
Consistency is key—NR begins boosting NAD+ levels within 24 hours, with substantial increases observed over days to weeks in a dose-dependent manner.
For optimal results, take at the same time each day as part of your longevity wellness routine.
Can be combined with other longevity supplements like resveratrol for synergistic effects.
Ingredients
Ingredients
Nicotinamide Riboside (as NR Hydrogen Malate) 500mg, Trimethylglycine (TMG) 250mg, Vegetable Cellulose (capsule), Microcrystalline Cellulose

ProHealth Longevity
The Only Clinically-Proven NMN That Works
In a double-blind study, their NMN increased NAD+ levels by 38% - equivalent to reversing biological age by 12 years. Third-party tested for purity against fake NMN flooding the market.
NR Pro 500 + TMG
Frequently Asked Questions
What makes Nicotinamide Riboside different from other NAD+ boosters?
Nicotinamide Riboside (NR) is a smaller molecule than NMN (Nicotinamide Mononucleotide), allowing it to easily pass through cell membranes without needing conversion.
While NMN must be converted to NR before entering cells, NR absorbs directly and then converts to NAD+ inside the cell through efficient enzymatic pathways.
Both are effective NAD+ boosters backed by research, but NR has been clinically proven in over 300 studies with a strong safety profile.
ProHealth uses NR Hydrogen Malate, an advanced form made without chemical solvents for superior purity.
Why is TMG included in this formula?
When your body metabolizes NAD+, it produces nicotinamide (NAM) which must be methylated and excreted through urine.
This process requires methyl groups—molecular units needed for DNA function, neurotransmitter production, and detoxification.
Taking NAD+ boosters can increase demand for methyl groups, potentially depleting your body's methyl pool.
TMG (Trimethylglycine) acts as a methyl donor, replenishing these groups to ensure your body has adequate reserves for all essential methylation functions.
This is the protocol recommended by leading longevity researchers like Dr. David Sinclair.
How long does it take to see results from NR supplementation?
NR begins boosting NAD+ levels within 24 hours of your first dose, with substantial increases observed over days to weeks in a dose-dependent manner.
Many users report feeling increased energy, improved mental clarity, and enhanced exercise performance within the first 2-4 weeks.
However, the most significant benefits for cellular health, DNA repair, and longevity pathways compound over time with consistent daily use.
Clinical studies typically measure meaningful improvements in mitochondrial function and metabolic markers after 8-12 weeks of supplementation.
Can I take this along with other supplements and medications?
NR Pro 500 + TMG can generally be combined with other longevity supplements like resveratrol, CoQ10, or pterostilbene for synergistic benefits.
In fact, many longevity experts recommend taking NR with resveratrol, as NR acts like fuel while resveratrol acts as the accelerator pedal for sirtuin activation.
However, if you're taking medications or have underlying health conditions, consult your healthcare provider before starting any new supplement.
Not recommended for pregnant or nursing women or children under 18.