• Multi-Biome™: Multi-Source probiotic tablets
  • Multi-Biome™: Multi-Source probiotic tablets
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Description

Two Types of Probiotics in One Formula

Multi-Biome combines two different kinds of probiotics that work together for complete gut health.

It includes spore-based probiotics (from soil) that are super tough and survive your stomach acid, plus live probiotics that start working right away.

You get 27 billion beneficial bacteria from six proven strains—so you only need one supplement instead of buying multiple bottles.

Smart Probiotic Selection

The formula includes three spore-based Bacillus strains that stay dormant until they reach your intestines, where they "wake up" and get to work.

It also has three live strains including Lactobacillus rhamnosus GG (one of the most studied probiotics in the world) and two other strains specifically chosen to help with histamine balance—important if you have histamine sensitivity.

All these probiotics crowd out bad bacteria while supporting the good ones.

Stays Fresh Without Refrigeration

Multi-Biome uses special delayed-release capsules that protect the probiotics through your stomach acid so they reach your intestines alive.

The bottle has advanced packaging that keeps everything fresh without needing refrigeration—perfect for travel.

All strains are backed by published research and the formula is free from major allergens (though it contains coconut-derived MCT).

How to use

Take 1 capsule once daily with or without food, or as directed by your healthcare professional.

If you're sensitive to probiotics or new to supplementation, consider starting with half a capsule for the first few days and gradually increasing to the full dose.

No refrigeration required—advanced desiccant-lined bottle technology maintains potency at room temperature.

Consult your healthcare provider before use if pregnant or nursing.

Ingredients

Lactobacillus rhamnosus (GG), Bacillus Subtilis (DE111®), Bacillus coagulans (BCP92), Bifidobacterium lactis (Bi-07), Lactobacillus salivarius (Ls-33), Bacillus coagulans (MTCC 5856), Rice Maltodextrin, Medium Chain Triglycerides (from coconut)

Multi-Biome™

Researched Nutritionals

Unique dual-action probiotic combining spore-based and live strain probiotics (27 billion CFU) for comprehensive gut health, histamine support, and immunit

  • Dual-Action Spore & Live Strain Synergy
  • Histamine & Immune Modulation
  • Advanced Survivability & No Refrigeration
  • Genomically Verified Research-Backed Strains
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Description

Two Types of Probiotics in One Formula

Multi-Biome combines two different kinds of probiotics that work together for complete gut health.

It includes spore-based probiotics (from soil) that are super tough and survive your stomach acid, plus live probiotics that start working right away.

You get 27 billion beneficial bacteria from six proven strains—so you only need one supplement instead of buying multiple bottles.

Smart Probiotic Selection

The formula includes three spore-based Bacillus strains that stay dormant until they reach your intestines, where they "wake up" and get to work.

It also has three live strains including Lactobacillus rhamnosus GG (one of the most studied probiotics in the world) and two other strains specifically chosen to help with histamine balance—important if you have histamine sensitivity.

All these probiotics crowd out bad bacteria while supporting the good ones.

Stays Fresh Without Refrigeration

Multi-Biome uses special delayed-release capsules that protect the probiotics through your stomach acid so they reach your intestines alive.

The bottle has advanced packaging that keeps everything fresh without needing refrigeration—perfect for travel.

All strains are backed by published research and the formula is free from major allergens (though it contains coconut-derived MCT).

How to use

Take 1 capsule once daily with or without food, or as directed by your healthcare professional.

If you're sensitive to probiotics or new to supplementation, consider starting with half a capsule for the first few days and gradually increasing to the full dose.

No refrigeration required—advanced desiccant-lined bottle technology maintains potency at room temperature.

Consult your healthcare provider before use if pregnant or nursing.

Ingredients

Lactobacillus rhamnosus (GG), Bacillus Subtilis (DE111®), Bacillus coagulans (BCP92), Bifidobacterium lactis (Bi-07), Lactobacillus salivarius (Ls-33), Bacillus coagulans (MTCC 5856), Rice Maltodextrin, Medium Chain Triglycerides (from coconut)

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Researched Nutritionals

Where Research Meets Real Clinical Results

Researched Nutritionals backs every formula with peer-reviewed, published clinical research. Founded in 2006, they invest heavily in university studies to prove efficacy.

Unlike brands that just claim quality, they publish actual data. Their Tri-Fortify glutathione and ATP360 formulas are clinically proven to work in real patients.
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Multi-Biome™

Frequently Asked Questions

What makes Multi-Biome different from other probiotics?

Most probiotics contain only one type: either live strains (Lactobacillus, Bifidobacterium) or spore-based strains (Bacillus).
Multi-Biome is unique because it combines both in one formula.
Spore-based strains survive harsh conditions, colonize effectively in the gut, and remain dormant until they reach the intestines.
Live strains provide immediate beneficial activity but are more fragile.
By combining both, you get the colonization benefits of spore-based probiotics plus the immediate activity of live strains—eliminating the need to take two separate probiotic supplements for comprehensive gut support.

Why is histamine support important in a probiotic?

Many probiotics actually produce histamine as a metabolic byproduct, which can be problematic for people with histamine intolerance, mast cell activation syndrome (MCAS), or chronic inflammatory conditions.
Multi-Biome's L. rhamnosus GG and Bifidobacterium lactis Bi-07 strains were specifically chosen because they support healthy histamine management rather than producing histamine.
This makes Multi-Biome suitable for individuals with histamine sensitivity who need probiotic support but have struggled with other formulas that worsened their symptoms.

Does this really not need refrigeration?

Correct—no refrigeration required. The spore-based Bacillus strains are naturally heat-stable and temperature-resistant (they're designed to survive in soil).
For the live strains, Multi-Biome uses two technologies: (1) delayed-release capsules that protect the strains from moisture and temperature fluctuations until ingestion, and (2) advanced desiccant-lined bottle technology that actively removes oxygen and moisture during storage.
This maintains potency at room temperature, making it convenient for travel, office use, or anywhere you can't refrigerate supplements.

Should I start with a full capsule or work up gradually?

If you're new to probiotics or have a sensitive digestive system, consider starting with half a capsule for the first few days, then gradually increase to a full capsule daily.
Some people experience temporary digestive adjustments (mild gas, bloating, or changes in bowel movements) when introducing probiotics, especially spore-based strains that actively remodel the gut microbiome.
These effects typically resolve within 2-3 days and indicate the probiotics are working.
If you tolerate probiotics well, you can start with the full one-capsule daily dose.
Always take consistently for best results—beneficial bacteria need regular reinforcement to maintain optimal populations.