Cytokines are signaling proteins your immune system produces to coordinate inflammatory responses during infections or injuries. They're supposed to turn on during a threat and turn off when the threat is gone. The problem occurs when pro-inflammatory cytokines (like IL-1, IL-6, IL-8, TNF-α, and NF-κB) get stuck in the "on position" after the immune challenge has resolved. This creates chronic low-grade inflammation that contributes to pain, poor sleep, cardiovascular stress, and accelerated aging. CytoQuel helps modulate these cytokines back to balanced levels through multiple anti-inflammatory pathways.

CytoQuel underwent an 8-week clinical human study published in the peer-reviewed Journal of Pain Research. The research showed statistically significant improvements in cytokine function, vascular health markers, and sleep quality. Most cytokine support supplements don't have this level of clinical validation—they're based on individual ingredient research rather than testing the actual formula. CytoQuel's published research demonstrates that this specific combination of ingredients, at these specific dosages, effectively supports healthy cytokine balance in humans.

CytoQuel is valuable in several situations: (1) During or after acute infections when inflammation needs to resolve, (2) For managing Herxheimer (die-off) reactions during treatment protocols for chronic infections like Lyme disease, (3) For ongoing support of chronic inflammatory conditions affecting joints, sleep, or overall comfort, (4) As part of a healthy aging protocol to prevent chronic cytokine elevation. Many practitioners use it alongside immune-supporting supplements—the immune support activates your defenses while CytoQuel helps ensure the inflammatory response resolves appropriately afterward.

Several ingredients in CytoQuel are fat-soluble, including curcumin (from CurcuWIN™ turmeric), tocotrienols, and resveratrol.
Taking with a meal that contains some healthy fats significantly improves absorption of these compounds. The CurcuWIN™ is already formulated for enhanced bioavailability, but food further optimizes absorption.
Additionally, NAC can sometimes cause mild stomach upset on an empty stomach, so taking with food minimizes any potential digestive sensitivity.
The 12mg of caffeine from black tea extract is minimal (about 1/10th of a cup of coffee), so it won't interfere with evening dosing if needed.