Description
Description
Calcium AKG Longevity provides 1000mg of calcium alpha-ketoglutarate, a naturally-occurring compound that's essential for cellular energy production but declines dramatically with age—dropping nearly 90% between ages 40 and 80.
This decline contributes to fatigue, cellular dysfunction, and accelerated aging. Since AKG isn't found in food, supplementation is the only way to restore youthful levels.
Remarkable human research results: In a groundbreaking 2021 study published in the journal Aging, 42 participants taking 1000mg of calcium AKG daily for an average of 7 months experienced an average 8-year reversal in biological age, measured using DNA methylation testing.
Biological age measures how old your cells actually are (not your birthday age), and this study showed people's cells were functioning like they were 8 years younger.
How it works in simple terms: Calcium AKG supports your body through multiple pathways. First, it's a key player in the Krebs cycle—the process your cells use to turn food into energy (ATP).
More AKG means better cellular energy and less fatigue.
Second, it activates autophagy, your body's cellular "recycling program" that removes damaged cells and proteins.
This cleanup process naturally slows with age, but Ca-AKG helps restore it.
Third, it supports DNA methylation—the process that controls which genes are turned "on" or "off" for healthy aging. Finally, it acts as a building block for glutathione (your body's master antioxidant) and collagen.
Proven in animal research too: Studies at the Buck Institute found that mice given Ca-AKG lived 12-20% longer, showed 41% better healthspan (years lived in good health), had stronger bones, better heart function, and reduced signs of frailty.
The calcium form provides better stability and absorption than standard AKG.
How to use
How to use
Take 2 capsules daily (1000mg total) in the morning with or without food, or as directed by your healthcare professional.
For optimal longevity benefits, maintain consistent daily use for at least 6-7 months.
Consider taking a biological age test (DNA methylation clock) before starting supplementation and again after 6-10 months to track your cellular age response.
Ingredients
Ingredients
Calcium Alpha-Ketoglutarate (Ca-AKG) 1000mg per serving, Organic Rice Flour, Vegetarian Capsule (Cellulose, Water)
Calcium AKG Longevity
Clinical-strength 1000mg calcium alpha-ketoglutarate shown to reverse biological age by 8 years in DNA methylation studies while supporting cellular energy
- Biological Age Reversal & DNA Methylation Support
- Enhanced Cellular Energy & Mitochondrial Function
- Autophagy Activation & Cellular Renewal
- Bone, Heart & Metabolic Health Support
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Description
Description
Calcium AKG Longevity provides 1000mg of calcium alpha-ketoglutarate, a naturally-occurring compound that's essential for cellular energy production but declines dramatically with age—dropping nearly 90% between ages 40 and 80.
This decline contributes to fatigue, cellular dysfunction, and accelerated aging. Since AKG isn't found in food, supplementation is the only way to restore youthful levels.
Remarkable human research results: In a groundbreaking 2021 study published in the journal Aging, 42 participants taking 1000mg of calcium AKG daily for an average of 7 months experienced an average 8-year reversal in biological age, measured using DNA methylation testing.
Biological age measures how old your cells actually are (not your birthday age), and this study showed people's cells were functioning like they were 8 years younger.
How it works in simple terms: Calcium AKG supports your body through multiple pathways. First, it's a key player in the Krebs cycle—the process your cells use to turn food into energy (ATP).
More AKG means better cellular energy and less fatigue.
Second, it activates autophagy, your body's cellular "recycling program" that removes damaged cells and proteins.
This cleanup process naturally slows with age, but Ca-AKG helps restore it.
Third, it supports DNA methylation—the process that controls which genes are turned "on" or "off" for healthy aging. Finally, it acts as a building block for glutathione (your body's master antioxidant) and collagen.
Proven in animal research too: Studies at the Buck Institute found that mice given Ca-AKG lived 12-20% longer, showed 41% better healthspan (years lived in good health), had stronger bones, better heart function, and reduced signs of frailty.
The calcium form provides better stability and absorption than standard AKG.
How to use
How to use
Take 2 capsules daily (1000mg total) in the morning with or without food, or as directed by your healthcare professional.
For optimal longevity benefits, maintain consistent daily use for at least 6-7 months.
Consider taking a biological age test (DNA methylation clock) before starting supplementation and again after 6-10 months to track your cellular age response.
Ingredients
Ingredients
Calcium Alpha-Ketoglutarate (Ca-AKG) 1000mg per serving, Organic Rice Flour, Vegetarian Capsule (Cellulose, Water)

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Calcium AKG Longevity
Frequently Asked Questions
What is Calcium AKG and why does it decline with age?
Calcium alpha-ketoglutarate (Ca-AKG) is a naturally-occurring metabolite that's essential for the Krebs cycle—the process your cells use to convert food into energy (ATP).
It also regulates DNA methylation, supports autophagy (cellular cleanup), and provides building blocks for important molecules like glutathione and collagen.
The problem is that AKG levels drop dramatically as you age, declining nearly 90% between ages 40 and 80.
This decline contributes to decreased energy, reduced cellular repair, and accelerated aging.
Since AKG isn't found in foods, supplementation is the only way to restore youthful levels.
What does "8-year biological age reversal" actually mean?
Biological age measures how old your cells actually are based on DNA methylation patterns, which is different from your chronological age (how many birthdays you've had).
In a published 2021 clinical study, 42 people taking 1000mg of calcium AKG daily for an average of 7 months showed their biological age decreased by an average of 8 years when measured using the TruAge DNA methylation test.
This means their cells were functioning like they were 8 years younger.
You can track this yourself using at-home biological age testing kits before and after supplementing for 6-10 months.
How long do I need to take it to see results?
The landmark clinical study showed significant biological age reversal after an average of 7 months of daily use at 1000mg.
Animal studies suggest benefits like increased lifespan and reduced frailty become apparent when supplementation begins in midlife and continues long-term.
For longevity benefits, think of Ca-AKG as a daily practice rather than a short-term intervention—consistent use for at least 6-12 months is recommended to see measurable changes in biological age testing and experience improvements in energy, vitality, and age-related health markers.
Is it safe and are there any side effects?
Calcium AKG has GRAS (Generally Recognized As Safe) status and clinical research shows no significant adverse effects even at doses up to 4.5 grams daily for as long as 3 years.
The 1000mg dose in this formula matches what was safely used in the biological age reversal study.
Because it's a naturally-occurring metabolite your body already produces, it's generally well-tolerated.
As with any supplement, consult your healthcare provider before starting, especially if you have kidney issues, take medications, or are pregnant or nursing.