Description
Description
HU58 is a powerful single-strain probiotic that contains a special type of "good bacteria" called Bacillus subtilis HU58.
This strain was originally found in a healthy person's gut and is much stronger than regular probiotics because it forms a protective shell that helps it survive your stomach acid and reach your intestines alive.
What makes HU58 special is that it can produce natural antibiotics that help fight harmful bacteria in your gut while supporting the good bacteria you need.
Clinical studies show it increases beneficial compounds called short-chain fatty acids by 40%, which help reduce inflammation and support a healthy gut lining.
Unlike regular probiotics that need refrigeration and often don't work, HU58's "spore" technology means it stays stable at room temperature and actually colonizes in your gut.
How to use
How to use
Take 1-2 capsules daily with a meal or as directed by your healthcare practitioner.
Start with 1 capsule daily for the first week, then increase to 2 capsules daily as tolerated.
Capsules may be opened and mixed into food or beverages for easy consumption.
Ingredients
Ingredients
Bacillus subtilis HU58 (10 billion CFU), Pharmaceutical grade cellulose, vegetable capsule (hydroxypropyl methylcellulose)
HU58™
High-potency single-strain spore probiotic with Bacillus subtilis HU58 for immune function, digestive health, and gut microbiome balance.
- Complete Digestive Survivability
- Enhanced SCFA Production
- Natural Antimicrobial Activity
- Multi-System Support
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Description
Description
HU58 is a powerful single-strain probiotic that contains a special type of "good bacteria" called Bacillus subtilis HU58.
This strain was originally found in a healthy person's gut and is much stronger than regular probiotics because it forms a protective shell that helps it survive your stomach acid and reach your intestines alive.
What makes HU58 special is that it can produce natural antibiotics that help fight harmful bacteria in your gut while supporting the good bacteria you need.
Clinical studies show it increases beneficial compounds called short-chain fatty acids by 40%, which help reduce inflammation and support a healthy gut lining.
Unlike regular probiotics that need refrigeration and often don't work, HU58's "spore" technology means it stays stable at room temperature and actually colonizes in your gut.
How to use
How to use
Take 1-2 capsules daily with a meal or as directed by your healthcare practitioner.
Start with 1 capsule daily for the first week, then increase to 2 capsules daily as tolerated.
Capsules may be opened and mixed into food or beverages for easy consumption.
Ingredients
Ingredients
Bacillus subtilis HU58 (10 billion CFU), Pharmaceutical grade cellulose, vegetable capsule (hydroxypropyl methylcellulose)

Microbiome Labs
Spore-Based Probiotics That Actually Survive
Their MegaSporeBiotic and Total Gut Restoration protocol reconditions rather than reseeds. No refrigeration needed, survives stomach acid, actually colonizes.
HU58™
Frequently Asked Questions
Why is HU58 called a "spore" probiotic and how is it different from regular probiotics?
HU58 forms a protective endospore shell that acts like natural armor, allowing it to survive manufacturing, shipping, stomach acid, and harsh digestive conditions.
Regular probiotics often die before reaching your intestines, while HU58 arrives 100% alive and begins working within 8 minutes of reaching your gut.
Can I take HU58 with antibiotics or other medications?
Yes, HU58's spore structure allows it to survive antibiotic treatment, making it ideal for post-antibiotic gut recovery.
However, consult your healthcare provider before combining with any medications, especially if you have compromised immune function or are taking immunosuppressive drugs.
How long does it take to see results with HU58?
Most people notice digestive improvements within 1-2 weeks, with optimal gut balance typically achieved after 4-8 weeks of consistent use.
The spores begin colonizing within 8 minutes of reaching your intestines, but full microbiome rebalancing takes time as beneficial changes accumulate.
Is it safe to take HU58 long-term or with other probiotics?
HU58 is safe for long-term use and actually enhances the effectiveness of other probiotics like MegaSporeBiotic.
It's been clinically studied for safety in various populations and can be taken during pregnancy, nursing, and by elderly individuals under healthcare guidance.